Description

Methyl 1,2,3,4-Tetrahydroisoquinoline-7-Carboxylate is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its functionalized tetrahydroisoquinoline scaffold, which serves as a critical intermediate for the development of novel pharmaceutical compounds and fine chemicals. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to synthesize complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of central nervous system (CNS) active agents, alkaloid derivatives, and other bioactive molecules.
• Agrochemical Research: Used as a building block for developing new crop protection agents and herbicides with novel modes of action.
• Organic Synthesis: Serves as a versatile synthon for constructing complex polycyclic frameworks and heterocyclic compounds in academic and industrial R&D.
• Material Science: Potential intermediate for the synthesis of specialty polymers, ligands, or organic electronic materials.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Methyl 1,2,3,4-Tetrahydroisoquinoline-7-Carboxylate
CAS No.	220247-50-7
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	7-(Methoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline; Methyl 7-isoquinolinecarboxylate, 1,2,3,4-tetrahydro-; 1,2,3,4-Tetrahydroisoquinoline-7-carboxylic acid methyl ester; 7-Carbomethoxy-1,2,3,4-tetrahydroisoquinoline; MTIQ-7-COOMe; 220247-50-7; Methyl THIQ-7-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 1,2,3,4-Tetrahydroisoquinoline-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.