Description

2-Pyridinemethanethiol,α-Methyl-,(Alphar)-(9Ci) is a specialized chiral organosulfur compound featuring a pyridine backbone. This chemical matters as a high-value building block and ligand in asymmetric synthesis, enabling the creation of enantiomerically pure pharmaceuticals and agrochemicals. It is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries for catalyst development and complex molecule synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic disorders.
• Catalyst Ligand: Used as a ligand in transition metal catalysis (e.g., palladium, rhodium) for asymmetric C-C and C-S bond-forming reactions.
• Agrochemical Synthesis: Employed in the research and production of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Fine Chemical Production: Acts as a precursor for other high-value specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Material Science Research: Investigated for the development of novel chiral materials and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A critical reagent for methodological development in organic and organometallic chemistry laboratories worldwide.

Basic Information

Product Name	2-Pyridinemethanethiol,α-Methyl-,(Alphar)-(9Ci)
CAS No.	220212-85-1
Molecular Formula	C7H9NS
Molecular Weight	139.22 g/mol
Synonyms	(R)-α-Methyl-2-pyridinemethanethiol; (R)-1-(Pyridin-2-yl)ethane-1-thiol; (R)-2-(1-Mercaptoethyl)pyridine; (R)-α-Methyl-2-pyridylmethanethiol; (R)-2-Pyridylethanethiol; (R)-H-MEPY; (AlphaR)-α-Methyl-2-pyridinemethanethiol; (9CI) Identifier
EINECS	Contact for details

Quality Control

Our 2-Pyridinemethanethiol,α-Methyl-,(Alphar)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and GC/HPLC for chemical purity, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C due to its easily oxidized nature. Keep the container in a cool, dry, well-ventilated place, away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.