Description

5-(Trifluoromethyl)-3-p-Tolyl-1H-Pyrazole is a high-value, fluorinated pyrazole derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring a trifluoromethyl group and a tolyl substituent, imparts unique electronic and steric properties essential for developing novel compounds with enhanced biological activity and material characteristics. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in areas targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Active Ingredient Synthesis: Used in the design and synthesis of novel herbicides, fungicides, and insecticides, leveraging the stability and lipophilicity conferred by the trifluoromethyl group.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and fluorinated components.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or tagging agent in the development of chemical probes for studying enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in multi-step synthesis projects requiring high-purity, specialized heterocyclic intermediates.

Basic Information

Product Name	5-(Trifluoromethyl)-3-p-Tolyl-1H-Pyrazole
CAS No.	219986-64-8
Molecular Formula	C11H9F3N2
Molecular Weight	226.20 g/mol
Synonyms	3-(4-Methylphenyl)-5-(trifluoromethyl)-1H-pyrazole; 5-(Trifluoromethyl)-3-(4-methylphenyl)-1H-pyrazole; 3-p-Tolyl-5-(trifluoromethyl)pyrazole; 1H-Pyrazole, 5-(trifluoromethyl)-3-(4-methylphenyl)-; 3-(4-Methylphenyl)-5-(trifluoromethyl)pyrazole; 5-Trifluoromethyl-3-p-tolyl-1H-pyrazole
EINECS	Contact for details

Quality Control

Every batch of 5-(Trifluoromethyl)-3-p-Tolyl-1H-Pyrazole is manufactured and tested under a strict quality management system. We provide comprehensive analytical documentation to ensure traceability and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality protocols are designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to fluoride/strong alkali conditions; ensure storage areas are segregated from such materials. Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.