Description

3-(4-Bromophenyl)-3-Chloropropan-1-Ol CAS NO 219745-24-1 is a versatile halogenated aromatic alcohol intermediate of significant importance in advanced organic synthesis. Its molecular structure, featuring both bromo and chloro substituents on a propanol backbone, makes it a valuable building block for constructing complex molecules. This compound is primarily sought after by research institutions and industrial R&D departments engaged in pharmaceutical development, agrochemical research, and the synthesis of specialty chemicals and liquid crystals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated phenyl group.
• Liquid Crystal Materials: Serves as a foundational unit for creating advanced liquid crystal compounds used in display technologies.
• Organic Light-Emitting Diodes (OLEDs): Employed in the development of electron-transport or host materials for OLED devices.
• Specialty Polymer Monomer: Acts as a functional monomer for introducing halogenated aromatic groups into polymers to modify properties like flame retardancy or refractive index.
• Cross-Coupling Reactions: The bromophenyl moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create more complex biaryl structures.

Basic Information

Product Name	3-(4-Bromophenyl)-3-Chloropropan-1-Ol
CAS No.	219745-24-1
Molecular Formula	C9H10BrClO
Molecular Weight	249.53 g/mol
Synonyms	3-Chloro-3-(4-bromophenyl)propan-1-ol; 1-Propanol, 3-chloro-3-(4-bromophenyl)-; 3-(4-Bromophenyl)-3-chloro-1-propanol; 3-Chloro-3-(p-bromophenyl)propan-1-ol; 3-(p-Bromophenyl)-3-chloropropanol; 3-Chloro-3-(4'-bromophenyl)propanol; (RS)-3-(4-Bromophenyl)-3-chloropropan-1-ol
EINECS	Contact for details

Quality Control

Our 3-(4-Bromophenyl)-3-Chloropropan-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent chemical identity. Standard quality parameters include assay by HPLC, identification by FT-IR and NMR, and control of related substances. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.