Description

1-Propanol,2-(Dimethylamino)-3-Mercapto-,(2S)-(9Ci) is a chiral, sulfur-containing amino alcohol derivative, identified by CAS number 219744-48-6. This compound is valued for its unique bifunctional structure, featuring both a tertiary amine and a thiol group, which makes it a versatile building block in advanced organic synthesis. It is primarily sought by research chemists and process development scientists in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis, ligand development, and as a precursor for complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring sulfur or amino alcohol motifs.
• Catalyst and Ligand Precursor: Used in the development of novel chiral catalysts and ligands for asymmetric hydrogenation and other enantioselective transformations.
• Peptidomimetic Research: Serves as a building block for creating peptide analogs and peptidomimetics in medicinal chemistry programs.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for introducing amine and thiol functionalities into specialty polymers.
• Chelating Agent Synthesis: A starting material for manufacturing chelating agents with potential applications in metal ion sequestration and catalysis.

Basic Information

Product Name	1-Propanol,2-(Dimethylamino)-3-Mercapto-,(2S)-(9Ci)
CAS No.	219744-48-6
Molecular Formula	C5H13NOS
Molecular Weight	135.23 g/mol
Synonyms	(2S)-2-(Dimethylamino)-3-mercapto-1-propanol; (S)-2-(Dimethylamino)-3-mercaptopropan-1-ol; 2-(Dimethylamino)-3-mercapto-1-propanol, (S)-; L-2-(Dimethylamino)-3-mercapto-1-propanol; 219744-48-6; Amino thiol derivative; Chiral amino thiol
EINECS	Contact for details

Quality Control

Our production of 1-Propanol,2-(Dimethylamino)-3-Mercapto-,(2S)-(9Ci) adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and enantiomeric excess meet the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing specific test results, including chiral purity by HPLC, is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation, minimize headspace and exposure to air after opening. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.