Description

1-Boc-6-Aminoindole is a protected aminoindole derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for building novel heterocyclic compounds. Its protected amine functionality provides strategic advantages in multi-step synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, particularly those targeting neurological disorders and oncology.
• Agrochemical Research: Used in the development of novel pesticides and herbicides with indole-based structures.
• Material Science: Serves as a precursor for functional organic materials and advanced polymers.
• Academic & R&D: Essential reagent in medicinal chemistry research for structure-activity relationship (SAR) studies and library synthesis.
• Peptidomimetics: Employed in the design and synthesis of indole-containing peptide analogs.
• Chemical Biology: Useful as a probe or linker in bioconjugation chemistry and probe development.

Basic Information

Product Name	1-Boc-6-Aminoindole
CAS No.	219508-62-0
Molecular Formula	C₁₃H₁₆N₂O₂
Molecular Weight	232.28 g/mol
Synonyms	1-[(tert-Butoxy)carbonyl]-1H-indol-6-amine; 6-Amino-1-Boc-indole; tert-Butyl 6-amino-1H-indole-1-carboxylate; 6-Aminoindole-1-carboxylic acid tert-butyl ester; 1H-Indol-6-amine, 1-[(1,1-dimethylethoxy)carbonyl]-; 1-Boc-6-amino-1H-indole; N-Boc-6-aminoindole; Boc-6-AI
EINECS	Contact for details

Quality Control

Our 1-Boc-6-Aminoindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We adhere to cGMP principles for pharmaceutical-grade intermediates, ensuring traceability and documentation for regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.