Description

Methyl 2-Oxo-1-Piperidin-4-Yl-2,3-Dihydro-1H-Benzoimidazole-5-Carboxylate CAS NO 219325-18-5 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within the fields of neurology and metabolic disorders.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates targeting specific biological pathways.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of novel compound libraries.
• API Synthesis: Serves as a core scaffold for the production of potential therapeutic agents, especially in central nervous system (CNS) and enzyme inhibitor research.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Biochemical Research: Utilized as a tool compound in biochemical assays to study protein-ligand interactions and enzyme functions.

Basic Information

Product Name	Methyl 2-Oxo-1-Piperidin-4-Yl-2,3-Dihydro-1H-Benzoimidazole-5-Carboxylate
CAS No.	219325-18-5
Molecular Formula	C14H17N3O3
Molecular Weight	275.30 g/mol
Synonyms	Methyl 1-(4-piperidinyl)-2,3-dihydro-2-oxo-1H-benzimidazole-5-carboxylate; 1-(4-Piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one-5-carboxylic Acid Methyl Ester; Methyl 2-oxo-1-(piperidin-4-yl)-2,3-dihydro-1H-benzo[d]imidazole-5-carboxylate; 219325-18-5; 1-Piperidin-4-yl-1,3-dihydro-benzimidazol-2-one-5-carboxylic Acid Methyl Ester; Methyl 1-(4-piperidyl)-2-oxo-2,3-dihydro-1H-benzimidazole-5-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 2-Oxo-1-Piperidin-4-Yl-2,3-Dihydro-1H-Benzoimidazole-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D and pre-clinical development. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥97% by HPLC), identity confirmation, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.