Description

[1-(tert-Butoxycarbonyl)Indol-3-Yl]Acetonitrile is a versatile and high-purity chemical building block, specifically an indole derivative protected with a Boc (tert-butoxycarbonyl) group. This compound matters as a critical intermediate in the synthesis of complex pharmaceutical molecules and advanced organic materials, offering a protected nitrogen site for selective reactions. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that utilize indole-based structures.
• Organic Synthesis Building Block: Serves as a protected precursor for constructing more complex heterocyclic compounds and natural product analogs in academic and industrial R&D.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors, ligands for catalysts, and specialty polymers.

Basic Information

Product Name	[1-(tert-Butoxycarbonyl)Indol-3-Yl]Acetonitrile
CAS No.	218772-62-4
Molecular Formula	C15H16N2O2
Molecular Weight	256.30 g/mol
Synonyms	1-Boc-3-cyanomethylindole; 1-(tert-Butoxycarbonyl)-3-(cyanomethyl)indole; 3-(Cyanomethyl)-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; 1-Boc-indole-3-acetonitrile; tert-Butyl 3-(cyanomethyl)-1H-indole-1-carboxylate; 1-N-Boc-3-indolylacetonitrile; Boc-Indole-3-CH2CN
EINECS	Contact for details

Quality Control

Our [1-(tert-Butoxycarbonyl)Indol-3-Yl]Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.