Description

3-Buten-2-One,4-(2-Methyl-1H-Benzimidazol-1-Yl)-,(3E)-(9Ci) is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular structure that combines a benzimidazole moiety with an α,β-unsaturated ketone. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers seeking to develop new therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzymatic pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating new fungicides or plant growth regulators with enhanced efficacy.
• Organic Synthesis: Utilized in academic and industrial labs for constructing complex heterocyclic compounds due to its reactive ketone functionality.
• Material Science Precursor: Potential use in the development of organic semiconductors or photoactive materials.
• Biochemical Probe Synthesis: Can be used to create labeled compounds or probes for biological assay development.

Basic Information

Item	Details
Product Name	3-Buten-2-One,4-(2-Methyl-1H-Benzimidazol-1-Yl)-,(3E)-(9Ci)
CAS No.	218436-89-6
Molecular Formula	C12H12N2O
Molecular Weight	200.24 g/mol
Synonyms	(3E)-4-(2-Methyl-1H-benzimidazol-1-yl)but-3-en-2-one; 4-(2-Methylbenzimidazol-1-yl)but-3-en-2-one; 1-(2-Methyl-1H-benzimidazol-1-yl)-3-buten-2-one; 4-(2-Methyl-1H-benzimidazol-1-yl)-3-buten-2-one; (E)-4-(2-Methyl-1H-benzimidazol-1-yl)but-3-en-2-one; 218436-89-6; But-3-en-2-one, 4-(2-methyl-1H-benzimidazol-1-yl)-, (3E)-
EINECS	Contact for details

Quality Control

Our 3-Buten-2-One,4-(2-Methyl-1H-Benzimidazol-1-Yl)-,(3E)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity, well-characterized intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.