Description

7-Azabicyclo[4.1.0]Heptan-2-Ol,4-(1-Methylethyl)-,(1R,2R,4R,6R)-Rel-(9Ci) is a high-purity, stereochemically defined bicyclic amine alcohol building block of significant interest in advanced organic synthesis. Its rigid, functionalized structure makes it a valuable intermediate for constructing complex molecular architectures with precise spatial orientation. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and catalyst design.

Application

• Pharmaceutical Intermediate: Serves as a key chiral scaffold or precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or anti-infective targets.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, or insecticides where its bicyclic structure can impart specific biological activity.
• Asymmetric Catalysis: Employed as a chiral ligand or a precursor for ligands in transition metal catalysis to induce enantioselectivity in synthetic transformations.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme function or protein-protein interactions due to its ability to mimic natural product frameworks.
• Advanced Material Research: Acts as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or mechanical properties.
• Process Chemistry & Scale-Up: Provides a defined starting point for optimizing synthetic routes from milligram to kilogram scale under current Good Manufacturing Practice (cGMP) guidelines.

Basic Information

Product Name	7-Azabicyclo[4.1.0]Heptan-2-Ol,4-(1-Methylethyl)-,(1R,2R,4R,6R)-Rel-(9Ci)
CAS No.	217310-20-8
Molecular Formula	C9H17NO
Molecular Weight	155.24 g/mol
Synonyms	(1R,2R,4R,6R)-rel-4-Isopropyl-7-azabicyclo[4.1.0]heptan-2-ol; 4-Isopropyl-7-azabicyclo[4.1.0]heptan-2-ol, (1R,2R,4R,6R)-rel-; rel-(1R,2R,4R,6R)-4-(1-Methylethyl)-7-azabicyclo[4.1.0]heptan-2-ol; Bicyclic amine alcohol intermediate; 7-Azabicyclo[4.1.0]heptan-2-ol, 4-(1-methylethyl)-, (1R,2R,4R,6R)-rel-
EINECS	Contact for details

Quality Control

Our 7-Azabicyclo[4.1.0]Heptan-2-Ol,4-(1-Methylethyl)-,(1R,2R,4R,6R)-Rel-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with every shipment. We support development under quality agreements and can supply material produced in compliance with ICH Q7 guidelines for advanced R&D and non-GMP pilot-scale campaigns.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.