Description

4-Chloro-1-Benzothiophene-2-Carbaldehyde is a versatile and high-value heterocyclic building block, specifically a functionalized benzothiophene derivative. This compound is critical for advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Acts as a building block for organic semiconductors, liquid crystals, and advanced polymers due to its electron-rich thiophene ring and aldehyde functionality.
• Chemical Synthesis: The reactive aldehyde and chloro groups make it a versatile scaffold for Suzuki-Miyaura, Sonogashira, and other cross-coupling reactions to create diverse chemical libraries.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where the benzothiophene structure imparts specific color and stability properties.

Basic Information

Product Name	4-Chloro-1-Benzothiophene-2-Carbaldehyde
CAS No.	216575-43-8
Molecular Formula	C9H5ClOS
Molecular Weight	196.65 g/mol
Synonyms	4-Chlorobenzo[b]thiophene-2-carboxaldehyde; 4-Chloro-1-benzothiophene-2-carboxaldehyde; 4-Chloro-benzo[b]thiophene-2-carbaldehyde; 2-Formyl-4-chlorobenzo[b]thiophene; 4-Chloro-2-formylbenzo[b]thiophene; 216575-43-8; 4-Chloro-benzo[b]thiophene-2-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 4-Chloro-1-Benzothiophene-2-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.