Description

Methyl 2-Amino-5-tert-Butylthiophene-3-Carboxylate is a high-purity, functionalized thiophene derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular architecture, which provides a versatile scaffold for constructing complex heterocyclic compounds and fine chemicals. This intermediate is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality raw materials for innovative applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the thiophene core for enhanced biological activity.
• Material Science Research: Serves as a monomer or functional unit in the development of conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for creating specialized heterocyclic dyes and organic pigments with specific coloristic properties.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for metal catalysis and organocatalysts used in asymmetric synthesis.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.

Basic Information

Product Name	Methyl 2-Amino-5-tert-Butylthiophene-3-Carboxylate
CAS No.	216574-71-9
Molecular Formula	C10H15NO2S
Molecular Weight	213.30 g/mol
Synonyms	2-Amino-5-tert-butylthiophene-3-carboxylic acid methyl ester; Methyl 5-tert-butyl-2-aminothiophene-3-carboxylate; 5-tert-Butyl-2-aminothiophene-3-carboxylic acid methyl ester; 3-Thiophenecarboxylic acid, 2-amino-5-(1,1-dimethylethyl)-, methyl ester; Methyl 2-amino-5-(tert-butyl)thiophene-3-carboxylate
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-Amino-5-tert-Butylthiophene-3-Carboxylate is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee specification adherence and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.