Description

8-Bromomethyl-4,4-Difluoro-1,3,5,7-Tetramethyl-4-Bora-3A,4A-Diaza-S-Indacene is a highly functionalized BODIPY (boron-dipyrromethene) derivative, serving as a critical building block for advanced fluorescent probes and labels. This compound matters for its reactive bromomethyl group, which enables facile covalent conjugation to biomolecules, polymers, or surfaces, while the BODIPY core provides exceptional photostability and high fluorescence quantum yield. It is essential for researchers and manufacturers in bioconjugation, flow cytometry, bioimaging, and materials science who require precise, bright, and stable fluorescent tags.

Application

• Bioconjugation Reagent: Used to label antibodies, proteins, peptides, and oligonucleotides for fluorescence-based assays (e.g., ELISA, Western blot).
• Flow Cytometry & Cell Sorting: Conjugated to specific ligands or antibodies for high-sensitivity detection and analysis of cell surface markers.
• Fluorescent Microscopy & Bioimaging: Serves as a core structure for developing organelle-specific or activity-based probes for live-cell and tissue imaging.
• Polymer & Materials Science: Incorporated into polymers, nanoparticles, or sensor materials to create smart, responsive fluorescent materials.
• Diagnostic Kit Development: A key component in the manufacture of lateral flow assays and other point-of-care diagnostic devices.
• Chemical Biology Research: Utilized as a tool to study protein-protein interactions, localization, and dynamics via fluorescence tagging.

Basic Information

Item	Detail
Product Name	8-Bromomethyl-4,4-Difluoro-1,3,5,7-Tetramethyl-4-Bora-3A,4A-Diaza-S-Indacene
CAS No.	216434-81-0
Molecular Formula	C14H14BBrF2N2
Molecular Weight	347.98 g/mol
Synonyms	8-Bromomethyl-BODIPY 493/503; 8-Bromomethyl-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene; BODIPY FL Br; BODIPY® FL Br; 8-(Bromomethyl)-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene; 8-Bromomethyl-4,4-difluoro-1,3,5,7-tetramethyl-2,6-diethyl-4-bora-3a,4a-diaza-s-indacene (common trade variant); Bromomethyl BODIPY FL
EINECS	Contact for details

Quality Control

Our 8-Bromomethyl-4,4-Difluoro-1,3,5,7-Tetramethyl-4-Bora-3A,4A-Diaza-S-Indacene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and light-sensitive; desiccants are recommended for long-term storage. Keep container tightly sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with reference structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0%
Fluorescence Emission	~503 nm (in suitable solvent)
Extinction Coefficient	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.