Description

trans-4-(β-Nitrovinyl)Benzeneboronic Acid CAS NO 216394-04-6 is a specialized boronic acid derivative featuring a nitrovinyl functional group, serving as a high-value synthetic intermediate in advanced organic chemistry. Its unique structure makes it a critical building block for constructing complex molecules, particularly in pharmaceutical research and materials science. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise and reliable intermediates for cross-coupling reactions and other sophisticated syntheses.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for targeted therapies.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a versatile boronic acid coupling partner for constructing biaryl and heterobiaryl structures central to many drug candidates.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science & OLED Development: Building block for creating advanced organic electronic materials, including emissive layers in OLEDs.
• Ligand Synthesis for Catalysis: Intermediate for preparing sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	trans-4-(β-Nitrovinyl)Benzeneboronic Acid
CAS No.	216394-04-6
Molecular Formula	C8H8BNO4
Molecular Weight	192.97 g/mol
Synonyms	trans-4-(2-Nitrovinyl)phenylboronic Acid; (E)-4-(2-Nitrovinyl)benzeneboronic Acid; 4-[(E)-2-Nitroethenyl]benzeneboronic Acid; p-(trans-2-Nitrovinyl)phenylboronic Acid; B-[4-[(E)-2-Nitroethenyl]phenyl]boronic Acid; 4-Nitrovinylphenylboronic Acid; trans-p-Nitrovinylphenylboronic Acid
EINECS	Contact for details

Quality Control

Our trans-4-(β-Nitrovinyl)Benzeneboronic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.