Description

6,8-Difluoro-7-Ethoxy-4-Methylcoumarin is a high-purity, synthetically derived fluorinated coumarin derivative. This compound is valued for its role as a versatile and critical pharmaceutical intermediate and advanced organic building block in complex synthesis. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and advanced material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in fluorinated compound libraries for oncology and CNS research.
• Fluorescent Probe & Dye Synthesis: Serves as a core structure for developing advanced fluorescent markers and sensors due to the coumarin scaffold's photophysical properties.
• Agrochemical Research: Used in creating new-generation pesticides and herbicides where the difluoro and ethoxy substitutions can enhance biological activity and stability.
• Organic Electronic Materials: Investigated as a building block for organic light-emitting diodes (OLEDs) and other optoelectronic materials.
• Chemical Biology Tool: Employed in designing activity-based probes and tags for studying enzymatic activity and protein labeling.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis, particularly in fluorination and cross-coupling chemistry.

Basic Information

Product Name	6,8-Difluoro-7-Ethoxy-4-Methylcoumarin
CAS No.	215868-24-9
Molecular Formula	C₁₂H₁₀F₂O₃
Molecular Weight	240.20 g/mol
Synonyms	7-Ethoxy-6,8-difluoro-4-methyl-2H-chromen-2-one; 6,8-Difluoro-7-ethoxy-4-methyl-2H-1-benzopyran-2-one; 4-Methyl-6,8-difluoro-7-ethoxycoumarin; 6,8-Difluoro-7-ethoxy-4-methylchromen-2-one; DFEMC; 215868-24-9 (CAS); 6,8-Difluoro-7-ethoxy-4-methyl-2-chromenone
EINECS	Contact for details

Quality Control

Our 6,8-Difluoro-7-Ethoxy-4-Methylcoumarin is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets exacting R&D and GMP-grade specifications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The product is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (by HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.