Description

2-Propenoicacid,3-(1H-Indol-6-Yl)-,(2E)- is a specialized indole-based acrylic acid derivative with the CAS registry number 215801-31-3. This compound serves as a crucial advanced pharmaceutical intermediate and a versatile building block for the synthesis of complex organic molecules. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Building block for developing new generation pesticides and plant growth regulators with enhanced efficacy.
• Polymer Chemistry: Monomer for creating specialty polymers with unique optical, electronic, or bioactive properties.
• Organic Synthesis: Versatile reagent for constructing complex heterocyclic frameworks and indole-containing compounds in academic and industrial R&D.
• Material Science: Used in the development of advanced functional materials, including organic semiconductors and photoresists.
• Bioconjugation: Potential use in linker chemistry for antibody-drug conjugates (ADCs) and other biopharmaceutical applications.

Basic Information

Product Name	2-Propenoicacid,3-(1H-Indol-6-Yl)-,(2E)-
CAS No.	215801-31-3
Molecular Formula	C11H9NO2
Molecular Weight	187.20 g/mol
Synonyms	(2E)-3-(1H-Indol-6-yl)acrylic acid; 3-(1H-Indol-6-yl)-2-propenoic acid, (2E)-; 6-Indolylacrylic acid; trans-3-(6-Indolyl)acrylic acid; (E)-3-(1H-Indol-6-yl)prop-2-enoic acid; 3-(6-Indolyl)acrylic acid; 215801-31-3; (E)-3-(1H-Indol-6-yl)acrylic acid
EINECS	Contact for details

Quality Control

Our production of 2-Propenoicacid,3-(1H-Indol-6-Yl)-,(2E)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to support cGMP compliance for advanced intermediates, ensuring traceability and documentation suitable for regulated industry use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere to prevent potential oxidation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.