Description

1,2,3,4-Tetrahydro-8-Isoquinolinecarbonitrile is a versatile and high-value heterocyclic nitrile building block used in advanced organic synthesis. This compound is critical for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories, agrochemical innovators, and fine chemical manufacturers for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of biologically active isoquinoline derivatives, including potential central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging the isoquinoline scaffold's bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials and advanced polymers due to its conjugated nitrile functionality.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	1,2,3,4-Tetrahydro-8-Isoquinolinecarbonitrile
CAS No.	215798-85-9
Molecular Formula	C10H10N2
Molecular Weight	158.20 g/mol
Synonyms	8-Cyano-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydroisoquinoline-8-carbonitrile; 1,2,3,4-Tetrahydro-8-cyanoisoquinoline; THIQ-8-CN; 8-CN-THIQ; Isoquinoline, 1,2,3,4-tetrahydro-8-cyano-; 215798-85-9 (CAS)
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-8-Isoquinolinecarbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP (current Good Manufacturing Practice) environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.