Description

6-Bromo-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is a versatile and high-value brominated tetrahydroisoquinoline derivative, primarily utilized as a critical synthetic intermediate in advanced organic chemistry. This compound is essential for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is particularly valuable for medicinal chemistry applications, including the synthesis of potential drug candidates targeting neurological and cardiovascular systems.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those with tetrahydroisoquinoline scaffolds.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• Organic Synthesis: Serves as a versatile precursor for introducing the bromo-tetrahydroisoquinoline moiety into larger molecular frameworks via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Agrochemical Development: Potential intermediate in the research and development of new crop protection agents and pesticides.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	6-Bromo-1,2,3,4-Tetrahydroisoquinoline Hydrochloride
CAS No.	215798-19-9
Molecular Formula	C9H10BrN·HCl
Molecular Weight	248.55 g/mol
Synonyms	6-Bromo-1,2,3,4-tetrahydroisoquinoline HCl; 6-Bromo-1,2,3,4-tetrahydroisoquinoline hydrochloride; 6-Bromotetrahydroisoquinoline hydrochloride; 1,2,3,4-Tetrahydro-6-bromoisoquinoline hydrochloride; 6-Bromo-THIQ HCl; 6-Br-THIQ·HCl; 215798-19-9; Isoquinoline, 6-bromo-1,2,3,4-tetrahydro-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 6-Bromo-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.