Description

1,2,3,4-Tetrahydro-Isoquinoline-5-Carbonitrile Hydrochloride is a high-purity, pharmaceutically relevant organic salt. This compound serves as a critical advanced intermediate or building block in the synthesis of complex molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging the isoquinoline scaffold.
• Organic Chemistry Research: Serves as a versatile precursor for heterocyclic chemistry, enabling the construction of complex nitrogen-containing ring systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and functional organic materials.

Basic Information

Product Name	1,2,3,4-Tetrahydro-Isoquinoline-5-Carbonitrile Hydrochloride
CAS No.	215794-24-4
Molecular Formula	C10H11N2•HCl
Molecular Weight	194.67 g/mol (Free base: 158.21 g/mol)
Synonyms	5-Cyano-1,2,3,4-tetrahydroisoquinoline hydrochloride; 1,2,3,4-Tetrahydro-5-cyanoisoquinoline HCl; 1,2,3,4-Tetrahydroisoquinoline-5-carbonitrile hydrochloride; THIQ-5-CN hydrochloride; 5-CN-THIQ•HCl; Isoquinoline-5-carbonitrile, 1,2,3,4-tetrahydro-, hydrochloride; 215794-24-4
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-Isoquinoline-5-Carbonitrile Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.