Description

1-(5-Bromo-3,4-Dihydro-2(1H)-Isoquinolinyl)-2,2,2-Trifluoro- Ethanone is a high-value trifluoroacetylated isoquinoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in enabling the precise construction of complex nitrogen-containing heterocycles, which are essential scaffolds in modern drug discovery and material science. This compound is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of advanced polymers and organic electronic materials.
• Chemical Biology Probe Synthesis: Utilized to create labeled compounds or molecular probes for studying biological pathways and protein interactions.
• Academic & Contract Research: Essential reagent for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	1-(5-Bromo-3,4-Dihydro-2(1H)-Isoquinolinyl)-2,2,2-Trifluoro- Ethanone
CAS No.	215794-11-9
Molecular Formula	C₁₁H₉BrF₃NO
Molecular Weight	308.10 g/mol
Synonyms	5-Bromo-1-(2,2,2-trifluoroacetyl)-1,2,3,4-tetrahydroisoquinoline; 1-(5-Bromo-3,4-dihydro-2(1H)-isoquinolinyl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(5-bromo-3,4-dihydro-1H-isoquinolin-2-yl)ethanone; 5-Bromo-2-(trifluoroacetyl)-1,2,3,4-tetrahydroisoquinoline; 1-(5-Bromo-1,2,3,4-tetrahydroisoquinolin-2-yl)-2,2,2-trifluoroethanone; Trifluoroacetyl-5-bromotetrahydroisoquinoline; 215794-11-9
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-3,4-Dihydro-2(1H)-Isoquinolinyl)-2,2,2-Trifluoro- Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 99.0% (High Purity Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.