Description

6-Bromo-1-Phenoxyisoquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its distinct brominated isoquinoline scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with potential therapeutic applications. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of small-molecule drugs, particularly those targeting central nervous system disorders and oncology.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a starting material for developing molecular probes to study biological pathways and protein functions.
• Organic Synthesis Building Block: Employed in cross-coupling reactions and other advanced organic transformations to create complex heterocyclic compounds.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.
• Material Science: Investigated as a monomer or precursor for specialty polymers and organic electronic materials.

Basic Information

Product Name	6-Bromo-1-Phenoxyisoquinoline
CAS No.	215453-25-1
Molecular Formula	C₁₅H₁₀BrNO
Molecular Weight	300.15 g/mol
Synonyms	6-Bromo-1-phenoxyisoquinoline; 1-Phenoxy-6-bromoisoquinoline; 6-Bromo-1-phenoxy-isoquinoline; Isoquinoline, 6-bromo-1-phenoxy-; 215453-25-1; 6-Bromo-1-phenoxy-isoquinoline; 6-Brom-1-phenoxyisochinolin (German)
EINECS	Contact for details

Quality Control

Our 6-Bromo-1-Phenoxyisoquinoline is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles for pharmaceutical intermediates, ensuring traceability and compliance with global regulatory expectations.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.