Description

5-(Bromomethyl)-2,3-Dihydro-1,4-Benzodioxine, 97% is a high-purity brominated benzodioxine derivative, serving as a versatile and critical building block in advanced organic synthesis. Its reactive bromomethyl group makes it an essential intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists in the life sciences and fine chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used to construct heterocyclic cores for new-generation herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts.
• Material Science Research: Employed in the development of organic electronic materials and advanced polymers.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and activity-based probes for biochemical studies.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	5-(Bromomethyl)-2,3-Dihydro-1,4-Benzodioxine, 97%
CAS No.	214894-89-0
Molecular Formula	C9H9BrO2
Molecular Weight	229.07 g/mol
Synonyms	5-(Bromomethyl)-1,4-benzodioxane; 2,3-Dihydro-5-(bromomethyl)-1,4-benzodioxin; 1,4-Benzodioxin, 2,3-dihydro-5-(bromomethyl)-; 5-Bromomethyl-2,3-dihydro-1,4-benzodioxine; 214894-89-0; 5-(Bromomethyl)benzo[d][1,3]dioxole (incorrect but common misnomer); Bromomethylbenzodioxane
EINECS	Contact for details

Quality Control

Our 5-(Bromomethyl)-2,3-Dihydro-1,4-Benzodioxine is manufactured under strict quality management protocols. Every batch is analyzed to ensure it meets the declared 97% minimum purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity confirmation, and impurity profiles via techniques such as HPLC, GC, NMR, and IR spectroscopy. Our quality systems are designed to support cGMP and ISO standards for traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Solubility	Soluble in common organic solvents (DCM, THF, DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.