Description

1-Phenyl-1-[4-(1-Piperidinyl)Phenyl]-2-Propyn-1-Ol, 97% is a high-purity, advanced pharmaceutical intermediate characterized by its unique tertiary alcohol and alkyne functional groups attached to a biphenyl-piperidine core structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and receptor-targeted therapies.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Organic Synthesis Building Block: Serves as a versatile precursor for constructing complex molecular architectures via Sonogashira coupling and other metal-catalyzed reactions.
• Ligand and Probe Development: Employed in the creation of chemical probes for studying enzyme and receptor function in biochemical assays.
• Fine Chemical Production: Utilized in the scaled-up manufacturing of specialty chemicals for advanced material science applications.

Basic Information

Product Name	1-Phenyl-1-[4-(1-Piperidinyl)Phenyl]-2-Propyn-1-Ol, 97%
CAS No.	214746-69-7
Molecular Formula	C20H21NO
Molecular Weight	291.39 g/mol
Synonyms	1-(4-Piperidin-1-ylphenyl)-1-phenylprop-2-yn-1-ol; 1-Phenyl-1-[4-(piperidin-1-yl)phenyl]prop-2-yn-1-ol; 1-(4-Piperidino)phenyl-1-phenyl-2-propyn-1-ol; 1-Phenyl-1-(4-piperidinophenyl)-2-propyn-1-ol; 1-(4-(Piperidin-1-yl)phenyl)-1-phenylprop-2-yn-1-ol; 214746-69-7; Tertiary Alkyne Alcohol Intermediate
EINECS	Contact for details

Quality Control

Our 1-Phenyl-1-[4-(1-Piperidinyl)Phenyl]-2-Propyn-1-Ol, 97% is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency meet the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.