Description

2-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is a high-value, organoboron building block essential for modern synthetic chemistry. This compound matters because it enables precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in pharmaceutical and advanced materials research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific pyridine-based scaffolds.
• Material Science & OLED Development: Serves as a building block for creating organic light-emitting diode (OLED) materials, liquid crystals, and conductive polymers.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for biochemical assays and diagnostic research.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura cross-coupling to introduce the pyridyl moiety into complex molecules.
• Academic & Contract Research: A vital reagent for methodology development and synthetic route exploration in academic and contract research organizations (CROs).

Basic Information

Item	Detail
Product Name	2-Bromo-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	214360-62-0
Molecular Formula	C11H15BBrNO2
Molecular Weight	268.96 g/mol
Synonyms	2-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 5-Bromo-2-pyridineboronic acid pinacol ester; (6-Bromopyridin-3-yl)boronic acid pinacol ester; 2-Bromo-5-pyridylboronic acid pinacol ester; 2-Bromo-5-(pinacolboryl)pyridine; 5-Bromo-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; CAS 214360-62-0
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request for quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.