Description

6-Fluoro-3,4-Dihydro-2H-Isoquinolin-1-One is a high-value fluorinated isoquinolinone derivative, serving as a critical building block in modern organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel pharmaceuticals and agrochemicals, where the fluorine atom is strategically incorporated to modulate biological activity and metabolic stability. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for creating new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine moiety enhances efficacy and environmental profile.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the synthesis of specialty chemicals and functional organic materials.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	6-Fluoro-3,4-Dihydro-2H-Isoquinolin-1-One
CAS No.	214045-84-8
Molecular Formula	C9H8FNO
Molecular Weight	165.17 g/mol
Synonyms	6-Fluoro-1,2,3,4-tetrahydroisoquinolin-1-one; 6-Fluoro-3,4-dihydro-1H-isoquinolin-1-one; 6-Fluoro-1-oxo-1,2,3,4-tetrahydroisoquinoline; 6-Fluoro-1-isoquinolinone; 6-Fluoro-3,4-dihydroisoquinolin-1(2H)-one; 6-Fluoro-1,2,3,4-tetrahydro-1-isoquinolinone; 214045-84-8
EINECS	Contact for details

Quality Control

Our 6-Fluoro-3,4-Dihydro-2H-Isoquinolin-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.