Description

3-Fluoro-4-(Trifluoromethyl)Benzyl Bromide is a high-value, multi-functional aromatic building block. This compound is essential for introducing the benzyl bromide moiety into complex molecules, enabling further functionalization. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and advanced intermediates. Its unique fluorine substitution pattern makes it a critical reagent for developing compounds with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to product efficacy and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing compounds used in electronic display technologies and organic light-emitting diodes.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with specific thermal and chemical resistance properties.
• Chemical Research & Development: A versatile reagent in organic synthesis for C-C and C-N bond formation reactions, such as Suzuki and Buchwald-Hartwig couplings.
• Fluorinated Surfactant Precursor: Used to synthesize surfactants and surface modifiers with unique hydrophobic and oleophobic characteristics.

Basic Information

Product Name	3-Fluoro-4-(Trifluoromethyl)Benzyl Bromide
CAS No.	213203-65-7
Molecular Formula	C8H5BrF4
Molecular Weight	257.03 g/mol
Synonyms	1-(Bromomethyl)-3-fluoro-4-(trifluoromethyl)benzene; α-Bromo-3-fluoro-4-(trifluoromethyl)toluene; (3-Fluoro-4-(trifluoromethyl)phenyl)methyl bromide; 3-Fluoro-α-bromo-4-(trifluoromethyl)toluene; 4-(Bromomethyl)-2-fluorobenzotrifluoride
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(Trifluoromethyl)Benzyl Bromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.