Description

trans-2-(2-Thiophenecarbonyl)-1-Cyclohexanecarboxylic Acid, 99 is a high-purity, advanced pharmaceutical intermediate characterized by its bicyclic structure incorporating both cyclohexane and thiophene moieties. This compound is critical for the synthesis of complex molecules, offering a versatile chiral building block for medicinal chemistry research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its specific stereochemistry can influence biological activity.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors and conductive polymers due to the electron-rich thiophene unit.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting exploratory synthetic chemistry.
• Custom Synthesis Building Block: Provides a foundational structure for custom chemical synthesis services targeting complex, high-value specialty chemicals.

Basic Information

Product Name	trans-2-(2-Thiophenecarbonyl)-1-Cyclohexanecarboxylic Acid, 99
CAS No.	212757-11-4
Molecular Formula	C12H14O3S
Molecular Weight	238.30 g/mol
Synonyms	trans-2-(2-Thienoyl)cyclohexane-1-carboxylic Acid; (1R,2R)-rel-2-(2-Thiophenecarbonyl)cyclohexanecarboxylic Acid; 2-(2-Thienoyl)cyclohexanecarboxylic Acid; 1-Cyclohexanecarboxylic acid, 2-(2-thienylcarbonyl)-, trans-; 212757-11-4; Thiophene-2-carboxylic acid cyclohexanone derivative
EINECS	Contact for details

Quality Control

Our trans-2-(2-Thiophenecarbonyl)-1-Cyclohexanecarboxylic Acid, 99 is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming the product meets the specified 99% purity grade and is suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.