Description

Bicyclo[3.1.0]Hex-2-Ene-6-Carbonitrile, 2-Methoxy-6-Methyl-4-Oxo-, (1R,5S,6S)-Rel- (9Ci) is a high-purity, stereochemically defined bicyclic nitrile building block of significant interest in advanced organic synthesis. Its complex, rigid molecular framework makes it a valuable chiral intermediate for constructing pharmacologically active compounds. This product is primarily needed by pharmaceutical R&D and process chemistry teams engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for complex small-molecule drugs.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to introduce the bicyclo[3.1.0]hexane scaffold into target molecules.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs due to its unique three-dimensional structure.
• Process Chemistry Development: Serves as a starting material or advanced intermediate in the scale-up and optimization of synthetic routes for candidate drugs.
• Fine Chemical Synthesis: Used in the production of specialized agrochemicals, flavors, fragrances, and other high-value chemicals requiring complex cyclic structures.
• Academic Research: A compound of interest in methodological studies focused on cyclopropane chemistry and ring-strain utilization.

Basic Information

Item	Detail
Product Name	Bicyclo[3.1.0]Hex-2-Ene-6-Carbonitrile, 2-Methoxy-6-Methyl-4-Oxo-, (1R,5S,6S)-Rel- (9Ci)
CAS No.	212609-31-9
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	(1R,5S,6S)-rel-2-Methoxy-6-methyl-4-oxobicyclo[3.1.0]hex-2-ene-6-carbonitrile; rel-(1R,5S,6S)-2-Methoxy-6-methyl-4-oxobicyclo[3.1.0]hex-2-ene-6-carbonitrile; Bicyclo[3.1.0]hex-2-ene-6-carbonitrile, 2-methoxy-6-methyl-4-oxo-, (1R,5S,6S)-rel-; 2-Methoxy-6-methyl-4-oxobicyclo[3.1.0]hex-2-ene-6-carbonitrile (rel-(1R,5S,6S)-form)
EINECS	Contact for details

Quality Control

Our Bicyclo[3.1.0]Hex-2-Ene-6-Carbonitrile, 2-Methoxy-6-Methyl-4-Oxo-, (1R,5S,6S)-Rel- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and stereochemical integrity, meeting the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity by HPLC, chiral purity, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This compound may be sensitive to prolonged exposure to light and moisture; handle and store under inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.