Description

2-(4-Aminophenyl)-1,2-Dihydro-1-Oxo-7-(2-Pyridinylmethoxy)-4-(3,4,5-Trimethoxyphenyl)-3-Isoquinolinecarboxylic Acid Methyl Ester Dihydrochloride is a high-purity, complex organic salt of significant interest in advanced pharmaceutical research and development. This compound serves as a critical chemical intermediate or reference standard for the synthesis and study of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and contract research organizations (CROs) engaged in developing new chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly in oncology and other therapeutic areas.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical research and manufacturing.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate biological pathways and mechanisms of action.
• Process Chemistry Development: Serves as a target molecule for optimizing synthetic routes and scaling up production processes.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry projects and the discovery of new bioactive compounds.

Basic Information

Product Name	2-(4-Aminophenyl)-1,2-Dihydro-1-Oxo-7-(2-Pyridinylmethoxy)-4-(3,4,5-Trimethoxyphenyl)-3-Isoquinolinecarboxylic Acid Methyl Ester Dihydrochloride
CAS No.	212498-37-8
Molecular Formula	C32H30N3O7 · 2HCl
Molecular Weight	657.53 g/mol (as free base: 568.60 g/mol)
Synonyms	7-(Pyridin-2-ylmethoxy)-4-(3,4,5-trimethoxyphenyl)-2-(4-aminophenyl)-1,2-dihydro-1-oxo-3-isoquinolinecarboxylic acid methyl ester dihydrochloride; Methyl 2-(4-aminophenyl)-1,2-dihydro-1-oxo-7-[(pyridin-2-yl)methoxy]-4-(3,4,5-trimethoxyphenyl)isoquinoline-3-carboxylate dihydrochloride; CAS 212498-37-8.
EINECS	Contact for details

Quality Control

Our 2-(4-Aminophenyl)-1,2-Dihydro-1-Oxo-7-(2-Pyridinylmethoxy)-4-(3,4,5-Trimethoxyphenyl)-3-Isoquinolinecarboxylic Acid Methyl Ester Dihydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.