Description

5-(5-Bromo-2-Thienyl)-1H-Tetrazole is a high-value, heterocyclic organic compound featuring a brominated thiophene ring fused to a tetrazole moiety. This unique molecular architecture makes it a critical pharmaceutical intermediate and versatile building block in advanced organic synthesis. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules with specific biological or electronic properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing tetrazole bioisosteres for improved metabolic stability and binding affinity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the tetrazole ring can act as a metabolically stable pharmacophore.
• Material Science & Coordination Chemistry: Serves as a ligand or building block for metal-organic frameworks (MOFs), polymers, and other functional materials due to its nitrogen-rich structure.
• Chemical Research & Development: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and in organic methodology development as a coupling partner or heterocyclic core.
• Energetic Materials Research: Investigated as a potential component in the development of high-nitrogen-content energetic compounds.

Basic Information

Product Name	5-(5-Bromo-2-Thienyl)-1H-Tetrazole
CAS No.	211943-12-3
Molecular Formula	C5H3BrN4S
Molecular Weight	230.08 g/mol
Synonyms	5-(5-Bromothiophen-2-yl)-1H-tetrazole; 5-(5-Bromo-2-thienyl)-1H-tetrazole; 5-(5-Bromothien-2-yl)tetrazole; 1H-Tetrazole, 5-(5-bromo-2-thienyl)-; 5-(5-Bromothiophene-2-yl)-1H-tetrazole; 5-(5-Bromo-thiophen-2-yl)-[1,2,3,4]tetrazole; 2-(1H-Tetrazol-5-yl)-5-bromothiophene
EINECS	Contact for details

Quality Control

Our 5-(5-Bromo-2-Thienyl)-1H-Tetrazole is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting critical specifications such as assay purity and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.