Description

4-Methylphenyl 2,3,4,6-Tetra-o-Acetyl-1-Thio-α-D-Mannopyranoside is a high-purity, protected thioglycoside building block essential for synthetic carbohydrate chemistry. This compound is a critical intermediate for the controlled synthesis of complex oligosaccharides and glycoconjugates, offering chemoselective reactivity for glycosidic bond formation. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, diagnostics, and chemical probes that target carbohydrate-mediated biological processes.

Application

• Glycoconjugate Synthesis: A key glycosyl donor for the solid-phase and solution-phase synthesis of biologically active glycoconjugates and neoglycoproteins.
• Oligosaccharide Assembly: Serves as a crucial mannose-derived building block for constructing complex, branched oligosaccharide libraries for structure-activity relationship (SAR) studies.
• Pharmaceutical Intermediates: Used in the research and development of carbohydrate-based vaccines, antiviral agents, and anti-inflammatory drugs.
• Chemical Biology Probes: Enables the creation of labeled carbohydrate probes for studying lectin-carbohydrate interactions and cell-surface glycan profiling.
• Material Science: Applied in the synthesis of carbohydrate-functionalized polymers and surfaces for biomedical and sensor applications.

Basic Information

Product Name	4-Methylphenyl 2,3,4,6-Tetra-o-Acetyl-1-Thio-α-D-Mannopyranoside
CAS No.	211801-79-5
Molecular Formula	C21H26O9S
Molecular Weight	454.49 g/mol
Synonyms	1-Thio-α-D-mannopyranoside, 2,3,4,6-tetra-O-acetyl-, 4-methylphenyl; p-Tolyl 2,3,4,6-tetra-O-acetyl-1-thio-α-D-mannopyranoside; 4-Methylphenyl 1-thio-α-D-mannopyranoside 2,3,4,6-tetraacetate; α-D-Mannopyranoside, 4-methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-; p-Tolyl 1-thio-α-D-mannopyranoside tetraacetate; Protected Thiomannoside; Acetylated Mannose Thioglycoside Donor
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and physical characteristics are available upon request. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.