Description

Benzene, 1-Bromo-3-Chloro-5-[(4-Methoxyphenyl)Methoxy]- is a high-purity, halogenated aromatic ether building block of significant interest in advanced organic synthesis. Its unique structure, featuring bromo and chloro substituents on a benzene ring linked to a methoxyphenylmethoxy group, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for constructing complex aryl ether scaffolds found in bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where its halogenated aromatic core provides structural diversity.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed in the creation of tagged molecules or inhibitors for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: The bromo and chloro substituents make it an excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form complex biaryl systems.
• Ligand and Catalyst Development: Utilized as a backbone for synthesizing novel chelating ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	Benzene, 1-Bromo-3-Chloro-5-[(4-Methoxyphenyl)Methoxy]-
CAS No.	210992-77-1
Molecular Formula	C14H12BrClO2
Molecular Weight	327.60 g/mol
Synonyms	1-Bromo-3-chloro-5-[(4-methoxyphenyl)methoxy]benzene; 3-Bromo-5-chlorophenyl 4-methoxybenzyl ether; 4-Methoxybenzyl 3-bromo-5-chlorophenyl ether; 5-[(4-Methoxyphenyl)methoxy]-1-bromo-3-chlorobenzene; (3-Bromo-5-chlorophenoxy)methyl-4-methoxybenzene
EINECS	Contact for details

Quality Control

Every batch of Benzene, 1-Bromo-3-Chloro-5-[(4-Methoxyphenyl)Methoxy]- is produced and analyzed under strict quality management protocols to ensure consistency and reliability for your critical research and development projects. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the presence of halogen substituents and an ether linkage, standard precautions for handling organic intermediates should be observed.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.