Description

1-((S)-2-Amino-Propyl)-1H-Indazol-6-Ol is a chiral indazole derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate or potential pharmacophore for the creation of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery programs, particularly those targeting central nervous system (CNS) disorders and other specialized therapeutic areas. The compound's defined stereochemistry and functional groups make it a valuable building block for medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly for CNS-targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies in academic and industrial R&D labs.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in API manufacturing.
• Biochemical Tool Compound: Employed in vitro and in vivo studies to investigate specific biological pathways and receptor interactions.
• Preclinical Development: Utilized in the early-stage development of potential new chemical entities (NCEs).

Basic Information

Product Name	1-((S)-2-Amino-Propyl)-1H-Indazol-6-Ol
CAS No.	210580-75-9
Molecular Formula	C11H15N3O
Molecular Weight	205.26 g/mol
Synonyms	(S)-1-(2-Aminopropyl)-1H-indazol-6-ol; 6-Hydroxy-1-[(1S)-2-aminopropyl]-1H-indazole; 1H-Indazol-6-ol, 1-[(1S)-2-aminopropyl]-; UNII-9J8F1108VN; 9J8F1108VN; (S)-6-Hydroxy-1-(2-aminopropyl)indazole; (S)-1-(2-Aminopropyl)-6-hydroxyindazole; 1-[(2S)-2-Aminopropyl]-1H-indazol-6-ol
EINECS	Contact for details

Quality Control

Our 1-((S)-2-Amino-Propyl)-1H-Indazol-6-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.