Description

tert-Butyl 3-(2-Bromoethyl)Piperidine-1-Carboxylate is a high-purity, protected piperidine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its reactive bromoethyl side chain and the Boc-protected amine, which allows for selective deprotection and further functionalization. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex nitrogen-containing heterocycles and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel piperidine-based drug candidates, including potential central nervous system (CNS) agents and receptor modulators.
• Agrochemical Research: Used in the development of new pesticides and herbicides where the piperidine scaffold imparts specific biological activity.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of molecular probes and activity-based protein profiling (ABPP) reagents.
• Material Science: Acts as a monomer or precursor for specialty polymers and advanced functional materials requiring specific nitrogen-containing motifs.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom synthesis projects and scale-up processes under cGMP conditions for clinical trial material production.

Basic Information

Product Name	tert-Butyl 3-(2-Bromoethyl)Piperidine-1-Carboxylate
CAS No.	210564-54-8
Molecular Formula	C12H22BrNO2
Molecular Weight	292.21 g/mol
Synonyms	1-Boc-3-(2-bromoethyl)piperidine; 1-(tert-Butoxycarbonyl)-3-(2-bromoethyl)piperidine; tert-Butyl 3-(2-bromoethyl)-1-piperidinecarboxylate; 3-(2-Bromoethyl)piperidine-1-carboxylic acid tert-butyl ester; 1-N-Boc-3-(2-bromoethyl)piperidine; 210564-54-8; Piperidine, 3-(2-bromoethyl)-, 1-(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(2-Bromoethyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting the results against our stringent in-house specifications. For advanced applications, we can supply material that meets the requirements for use in cGMP environments upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.