Description

n-(1,2,3,4-Tetrahydroisoquinolin-5-Yl)Methanesulfonamide Hydrochloride is a high-purity organic compound with the CAS number 210538-75-3, serving as a critical building block in advanced pharmaceutical research and development. This compound is valued for its role as a key synthetic intermediate in the creation of novel therapeutic agents, particularly within the central nervous system (CNS) and oncology drug discovery pipelines. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic entities.
• API Development: Serves as a building block in the development of Active Pharmaceutical Ingredients (APIs), particularly for compounds with tetrahydroisoquinoline scaffolds.
• Biochemical Research: Employed as a tool compound in biochemical assays and pharmacological studies.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis for creating complex, high-value specialty chemicals.

Basic Information

Product Name	n-(1,2,3,4-Tetrahydroisoquinolin-5-Yl)Methanesulfonamide Hydrochloride
CAS No.	210538-75-3
Molecular Formula	C10H15ClN2O2S
Molecular Weight	262.76 g/mol
Synonyms	5-(Methanesulfonamido)-1,2,3,4-tetrahydroisoquinoline hydrochloride; N-(1,2,3,4-Tetrahydro-5-isoquinolinyl)methanesulfonamide hydrochloride; Methanesulfonamide, N-(1,2,3,4-tetrahydro-5-isoquinolinyl)-, hydrochloride; 210538-75-3; 5-Amino-1,2,3,4-tetrahydroisoquinoline methanesulfonamide hydrochloride; TIQM Hydrochloride
EINECS	Contact for details

Quality Control

Our n-(1,2,3,4-Tetrahydroisoquinolin-5-Yl)Methanesulfonamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.