Description

3-Amino-2-Cyano-5-(4-Fluorophenyl)Thiophene is a high-value, multi-functional heterocyclic building block featuring a thiophene core with strategically positioned amino, cyano, and fluorophenyl substituents. This compound matters for its role as a critical intermediate in the synthesis of complex organic molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene and fluorophenyl motifs.
• Material Science Research: Serves as a building block for organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich thiophene structure.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where the amino and cyano groups facilitate chromophore development.
• Chemical Biology Probe Development: Utilized as a scaffold for creating molecular probes and fluorescent tags for biochemical and cellular imaging applications.

Basic Information

Item	Detail
Product Name	3-Amino-2-Cyano-5-(4-Fluorophenyl)Thiophene
CAS No.	210356-63-1
Molecular Formula	C11H7FN2S
Molecular Weight	218.25 g/mol
Synonyms	5-(4-Fluorophenyl)-3-amino-2-thiophenecarbonitrile; 3-Amino-5-(4-fluorophenyl)thiophene-2-carbonitrile; 2-Cyano-3-amino-5-(4-fluorophenyl)thiophene; 3-Amino-2-cyano-5-(p-fluorophenyl)thiophene; 210356-63-1; 5-(4-Fluorophenyl)-3-aminothiophene-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 3-Amino-2-Cyano-5-(4-Fluorophenyl)Thiophene is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.