Description

(R)-3-(Pyrrolidin-2-Yl)Pyridine Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate. This compound is critical for the research and development of novel therapeutics, particularly in the field of central nervous system (CNS) and neurological disorders. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug molecules targeting nicotinic acetylcholine receptors.
• Neurological Research: Used in the development of potential treatments for conditions such as Alzheimer's disease, Parkinson's disease, and cognitive disorders.
• Chemical Synthesis: Serves as a versatile building block for creating libraries of novel compounds in medicinal chemistry for high-throughput screening.
• Asymmetric Catalysis: Employed in research for developing new chiral ligands or catalysts due to its defined stereochemistry.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	(R)-3-(Pyrrolidin-2-Yl)Pyridine Hydrochloride
CAS No.	210094-28-3
Molecular Formula	C9H13ClN2
Molecular Weight	184.67 g/mol
Synonyms	(R)-3-(2-Pyrrolidinyl)pyridine hydrochloride; (R)-3-Pyrrolidin-2-yl-pyridine hydrochloride; (R)-Anabasine hydrochloride; (2R)-3-(2-Pyrrolidinyl)pyridine monohydrochloride; (R)-3-(1-Azabicyclo[2.2.0]hex-2-yl)pyridine hydrochloride (incorrect but sometimes used); (R)-Nornicotine analog hydrochloride; (R)-Pyrrolidinylpyridine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-3-(Pyrrolidin-2-Yl)Pyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.