Description

5-(1-Piperazinyl)-Isoquinoline Hcl is a high-purity organic compound, specifically a piperazinyl-substituted isoquinoline hydrochloride salt, that serves as a critical building block in advanced chemical synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with potential biological activity. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on medicinal chemistry and the discovery of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the privileged pharmacophore structures of piperazine and isoquinoline.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization programs to explore structure-activity relationships (SAR) and develop new chemical entities.
• Agrochemical Synthesis: Serves as a building block for developing new crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized compounds under cGMP conditions.
• Academic Research: Employed in university and institutional laboratories for fundamental organic synthesis projects and the development of new methodologies.

Basic Information

Product Name	5-(1-Piperazinyl)-Isoquinoline Hcl
CAS No.	209733-17-5
Molecular Formula	C13H16ClN3
Molecular Weight	249.74 g/mol
Synonyms	5-(Piperazin-1-yl)isoquinoline hydrochloride; 1-(Isoquinolin-5-yl)piperazine hydrochloride; 5-Piperazinylisoquinoline HCl; Isoquinoline, 5-(1-piperazinyl)-, hydrochloride; 209733-17-5; 5-(1-Piperazinyl)isoquinoline monohydrochloride
EINECS	Contact for details

Quality Control

Every batch of 5-(1-Piperazinyl)-Isoquinoline Hcl is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.