Description

5-Ethyl-3-[[(2R)-1-Methyl-2-Pyrrolidinyl]Methyl]-1H-Indole is a chiral indole derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a sophisticated building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly in central nervous system (CNS) and receptor-targeted drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective synthesis due to its defined (R)-configuration at the pyrrolidinyl methyl center.
• Biochemical Research: Potential use as a ligand or probe in biochemical assays and for studying enzyme-substrate interactions.
• Fine Chemical Production: Serves as a specialized intermediate in the multi-step synthesis of high-value, complex organic molecules for various industrial applications.

Basic Information

Product Name	5-Ethyl-3-[[(2R)-1-Methyl-2-Pyrrolidinyl]Methyl]-1H-Indole
CAS No.	209682-64-4
Molecular Formula	C16H22N2
Molecular Weight	242.36 g/mol
Synonyms	5-Ethyl-3-[(2R)-1-methylpyrrolidin-2-ylmethyl]-1H-indole; (R)-5-Ethyl-3-(1-methylpyrrolidin-2-ylmethyl)-1H-indole; 1H-Indole, 5-ethyl-3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-; 209682-64-4; (R)-enantiomer of 5-Ethyl-3-(1-methyl-2-pyrrolidinylmethyl)indole
EINECS	Contact for details

Quality Control

Our 5-Ethyl-3-[[(2R)-1-Methyl-2-Pyrrolidinyl]Methyl]-1H-Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure identity, potency, and the absence of critical impurities. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.