Description

1-Chloro-6-Methylisoquinoline is a versatile halogenated isoquinoline derivative, a key building block in advanced organic synthesis. Its molecular structure makes it a critical intermediate for the development of pharmaceuticals and agrochemicals, particularly in the creation of active pharmaceutical ingredients (APIs) and complex heterocyclic compounds. This high-purity intermediate is essential for research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging the isoquinoline scaffold for biological activity.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in catalytic processes, including cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or light-emitting components, due to its conjugated system.
• Chemical Biology Probe Synthesis: Utilized to build molecular probes for studying enzyme function and biological pathways in academic and industrial research settings.

Basic Information

Product Name	1-Chloro-6-Methylisoquinoline
CAS No.	209286-73-7
Molecular Formula	C10H8ClN
Molecular Weight	177.63 g/mol
Synonyms	6-Methyl-1-chloroisoquinoline; 1-Chloro-6-methyl-isoquinoline; Isoquinoline, 1-chloro-6-methyl-; 1-Chloro-6-methylisoquinoline; 1-Chloro-6-methyl-isoquinoline; 209286-73-7 (CAS); 6-Methyl-1-chloro-isoquinoline
EINECS	Contact for details

Quality Control

Our 1-Chloro-6-Methylisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.