Description

3S-1,2,3,4-Tetrahydro-β-Carboline-3-Carboxylic Acids is a high-purity chiral building block and a key synthetic intermediate in advanced organic chemistry. This compound is valued for its rigid, polycyclic structure which serves as a privileged scaffold in medicinal chemistry for drug discovery and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly those targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex alkaloids and potential drug candidates with neurological activity.
• Medicinal Chemistry Research: Serves as a core scaffold for constructing libraries of compounds in high-throughput screening for new biological targets.
• Asymmetric Synthesis: Used as a chiral starting material or auxiliary in stereoselective synthesis due to its defined 3S configuration.
• Biochemical Research: Employed in studies of enzyme inhibition and receptor-ligand interactions related to tetrahydro-β-carboline pharmacology.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	3S-1,2,3,4-Tetrahydro-β-Carboline-3-Carboxylic Acids
CAS No.	209169-30-2
Molecular Formula	C₁₂H₁₂N₂O₂
Molecular Weight	216.24 g/mol
Synonyms	(3S)-1,2,3,4-Tetrahydro-β-carboline-3-carboxylic acid; (S)-1,2,3,4-Tetrahydro-β-carboline-3-carboxylic acid; (S)-THCA; (S)-1,2,3,4-Tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylic acid; L-Tryptophan-derived β-carboline; 3S-THCA; (S)-Tryptoline-3-carboxylic acid; (3S)-1,2,3,4-Tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3S-1,2,3,4-Tetrahydro-β-Carboline-3-Carboxylic Acids is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation, to ensure it meets stringent specifications for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.