Description

5-Fluoro-3-(2-nitrovinyl)indole is a high-purity, synthetically valuable indole derivative characterized by its unique fluorinated and nitrovinyl functional groups. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the development of novel bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for drug discovery and fine chemical production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex indole-based drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in developing novel fungicides and herbicides, leveraging the bioactivity of the fluorinated indole scaffold.
• Organic Synthesis Building Block: The reactive nitrovinyl group makes it valuable for cycloaddition reactions and the construction of polyheterocyclic compounds.
• Material Science Precursor: Employed in the research and development of organic electronic materials and fluorescent dyes.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme inhibition and receptor binding.

Basic Information

Product Name	5-Fluoro-3-(2-nitrovinyl)indole
CAS No.	208645-53-8
Molecular Formula	C10H7FN2O2
Molecular Weight	206.18 g/mol
Synonyms	3-(2-Nitrovinyl)-5-fluoro-1H-indole; 5-Fluoro-3-(2-nitroethenyl)-1H-indole; 1H-Indole, 5-fluoro-3-(2-nitroethenyl)-; 5-Fluoro-3-nitrostyrylindole; 5-Fluoro-β-nitrostyrylindole; 5-Fluoroindole-3-acrylonitrile N-oxide derivative
EINECS	Contact for details

Quality Control

Our 5-Fluoro-3-(2-nitrovinyl)indole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment ensures the material is suitable for demanding research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.