Description

3-Methyl-D3-1,1-Diphenylurea is a deuterium-labeled isotopologue of a key urea derivative, where three hydrogen atoms are replaced by deuterium, providing a stable isotopic label. This compound is primarily valued as a crucial internal standard and tracer in quantitative mass spectrometry and metabolic studies, ensuring high analytical accuracy and reproducibility. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors who require precise analytical tools for method development, pharmacokinetics, and degradation pathway analysis.

Application

• Internal Standard for LC-MS/MS: Used as a high-purity reference standard in liquid chromatography-tandem mass spectrometry for the accurate quantification of parent compounds and metabolites in complex biological matrices.
• Metabolic Pathway Tracing: Serves as a stable isotopic tracer in drug metabolism and pharmacokinetics (DMPK) studies to elucidate biotransformation pathways.
• Pharmaceutical R&D: Employed in the development and validation of analytical methods for new chemical entities (NCEs) and generic drugs.
• Environmental Fate Studies: Applied in agrochemical research to track the environmental degradation and persistence of chemical agents.
• Chemical Synthesis Research: Acts as a labeled building block or intermediate in the synthesis of more complex deuterated compounds for various research applications.
• Quality Control & Assurance: Utilized in GMP and GLP environments to ensure batch-to-batch consistency and purity of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	3-Methyl-D3-1,1-Diphenylurea
CAS No.	208107-10-2
Molecular Formula	C14D3H11N2O
Molecular Weight	229.28 g/mol
Synonyms	1,1-Diphenyl-3-(methyl-d3)urea; N,N-Diphenyl-N'-(methyl-d3)urea; 3-(Methyl-d3)-1,1-diphenylurea; Deuterated 3-Methyl-1,1-diphenylurea; [Methyl-d3]-Diphenylurea; (Methyl-d3)carbanilide; Urea, 1,1-diphenyl-3-(methyl-d3)-; Isotopically Labeled Diphenylurea Derivative
EINECS	Contact for details

Quality Control

Our 3-Methyl-D3-1,1-Diphenylurea is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and mass spectrometry, to confirm identity, chemical purity, and deuterium incorporation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting compliance with GLP and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.