Description

(-)-3-(Trifluoroacetyl)Camphor is a high-value, enantiomerically pure chiral building block and ligand precursor, distinguished by its camphor skeleton and trifluoroacetyl functional group. This compound matters for its critical role in asymmetric synthesis, where it serves as a versatile intermediate for creating complex molecules with high stereochemical control. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for applications requiring precise chirality.

Application

• Asymmetric Synthesis: A key chiral auxiliary or ligand precursor in enantioselective catalytic reactions, including alkylations and aldol condensations.
• Pharmaceutical Intermediates: Used in the research and development of active pharmaceutical ingredients (APIs) where the camphor scaffold imparts specific biological activity or stereochemistry.
• Agrochemical Synthesis: Employed in creating chiral pesticides and herbicides that require specific enantiomers for optimal efficacy and environmental safety.
• Material Science Research: Acts as a precursor for developing chiral stationary phases in chromatography or novel chiral organic frameworks.
• Coordination Chemistry: Useful for synthesizing metal-organic complexes and catalysts due to its potential bidentate coordination sites.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process optimization studies.

Basic Information

Product Name	(-)-3-(Trifluoroacetyl)Camphor
CAS No.	207742-84-5
Molecular Formula	C₁₂H₁₅F₃O₂
Molecular Weight	248.24 g/mol
Synonyms	(-)-3-Trifluoroacetylcamphor; (1R,4S)-1,7,7-Trimethyl-3-(2,2,2-trifluoroacetyl)bicyclo[2.2.1]heptan-2-one; (1R)-3-[(Trifluoroacetyl)camphor]; L-3-Trifluoroacetylcamphor; (1R,4S)-3-(Trifluoroacetyl)camphor; TFAC; 3-TFAC
EINECS	Contact for details

Quality Control

Our (-)-3-(Trifluoroacetyl)Camphor is produced under strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC, NMR, and GC-MS, to confirm identity, purity, and the absence of critical impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We adhere to cGMP principles where applicable to support our customers in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.