Description

o-Toluic-D7 Acid CAS NO 207742-73-2 is a deuterium-labeled isotopologue of o-toluic acid, where seven hydrogen atoms are replaced by deuterium. This high isotopic purity is critical for applications requiring non-radioactive isotopic tracing and as an internal standard in quantitative mass spectrometry. It is an essential material for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise analytical tools and labeled precursors.

Application

• Internal Standard for Quantitative Analysis: Used as a deuterated internal standard in LC-MS and GC-MS for the accurate quantification of o-toluic acid and related compounds in complex matrices.
• Metabolic and Pharmacokinetic Studies: Serves as a stable isotope tracer in drug metabolism and absorption, distribution, metabolism, and excretion (ADME) research.
• Deuterated Pharmaceutical Intermediate: Acts as a key labeled building block in the synthesis of deuterated drug candidates, which can offer improved metabolic profiles.
• NMR Spectroscopy Solvent & Reagent: Employed as a shift reagent or in solvent systems for nuclear magnetic resonance (NMR) spectroscopy due to its deuterium content.
• Mechanistic Reaction Studies: Utilized in chemical reaction mechanism elucidation to track the fate of specific atoms or molecular fragments.
• Environmental Fate Analysis: Applied in tracing the environmental degradation pathways of toluic acid derivatives.

Basic Information

Product Name	o-Toluic-D7 Acid
CAS No.	207742-73-2
Molecular Formula	C8D7HO2
Molecular Weight	141.20 g/mol
Synonyms	2-Methylbenzoic-2,3,4,5,6-d5-acid-d2; 2-Methyl-d7-benzoic Acid; Deutero-o-Toluic Acid; (2-Methylphenyl-d7)carboxylic Acid; o-Toluic-d7 Acid; 2-Methylbenzoic-d7 Acid; Benzoic-d7 Acid, 2-methyl-; 2-(Methyl-d3)benzoic-3,4,5,6-d4 Acid
EINECS	Contact for details

Quality Control

Our o-Toluic-D7 Acid is manufactured under strict quality systems to ensure high chemical and isotopic purity. Each batch is characterized by NMR, MS, and HPLC to confirm identity, chemical purity, and deuterium incorporation. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically ≥98 atom % D), chemical purity (by HPLC), and other relevant specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from strong bases, oxidizing agents, and sources of ignition. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (NMR/MS)	≥98 atom % D
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.