Description

n-(2-Carboxyethyl)-n-[2-(2,5-Dihydro-2,5-Dioxo-1H-Pyrrol-1-yl)ethyl]-β-Alanine is a specialized functionalized amino acid derivative featuring both a carboxylic acid group and a maleimide moiety. This unique bifunctional structure makes it a valuable intermediate for creating covalent linkages in advanced material science and bioconjugation applications. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical, polymer, and life sciences sectors for synthesizing targeted drug delivery systems, functional polymers, and diagnostic reagents.

Application

• Bioconjugation Linker: A key intermediate for attaching peptides, proteins, or antibodies to other molecules, surfaces, or nanoparticles via the maleimide-thiol "click" chemistry.
• Polymer Modification: Used to introduce reactive sites or charged groups into polymer backbones to create smart materials, hydrogels, or coatings with specific functionalities.
• Pharmaceutical Intermediate: Serves as a building block in the synthesis of targeted prodrugs or antibody-drug conjugates (ADCs) for oncology and other therapeutic areas.
• Surface Functionalization: Enables the covalent immobilization of biomolecules on biosensor chips, diagnostic assay plates, and other medical device surfaces.
• Cross-linking Agent: Acts as a heterobifunctional cross-linker to create stable networks in advanced material formulations.
• Research & Development: A versatile tool compound for academic and industrial research in chemical biology and materials science.

Basic Information

Product Name	n-(2-Carboxyethyl)-n-[2-(2,5-Dihydro-2,5-Dioxo-1H-Pyrrol-1-yl)ethyl]-β-Alanine
CAS No.	207612-84-8
Molecular Formula	C12H16N2O6
Molecular Weight	284.27 g/mol
Synonyms	3-[2-2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethylamino]propanoic acid; N-(2-Carboxyethyl)-N-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]-β-alanine; Maleimide-PEG2-acid; Maleimide-C2-acid; β-Alanine, N-(2-carboxyethyl)-N-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]-; 1-(2-((3-Carboxypropyl)(2-carboxyethyl)amino)ethyl)-1H-pyrrole-2,5-dione; Maleimide-PEG2-C2-acid; Bifunctional Maleimide Acid Linker
EINECS	Contact for details

Quality Control

Our production of n-(2-Carboxyethyl)-n-[2-(2,5-Dihydro-2,5-Dioxo-1H-Pyrrol-1-yl)ethyl]-β-Alanine adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and precise titration methods. We provide Certificates of Analysis (COA) with detailed specifications to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) for long-term stability. This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.