Description

1-(Methyl-D3)-4-Phenylpyridinium Iodide is a deuterated quaternary ammonium salt, a high-value isotopically labeled compound essential for advanced research and development. Its core value lies in providing a stable, non-exchangeable deuterium label, which is critical for mechanistic studies, metabolic pathway tracing, and analytical method development using techniques like mass spectrometry. This product is primarily needed by pharmaceutical researchers, agrochemical developers, and academic institutions engaged in sophisticated organic synthesis, pharmacokinetics, and deuterium labeling applications.

Application

• Pharmaceutical Research & Development: Used as a key intermediate or reference standard in the synthesis of deuterated drug candidates for improved metabolic stability and pharmacokinetic studies.
• Metabolic Pathway Tracing: Serves as a stable, isotopically labeled tracer in mass spectrometry-based studies to investigate drug metabolism and biochemical pathways.
• Analytical Chemistry: Employed as an internal standard or calibrant in quantitative LC-MS and GC-MS analyses to enhance accuracy and precision.
• Mechanistic Organic Chemistry: Acts as a probe or reagent in reaction mechanism elucidation, leveraging the kinetic isotope effect (KIE) of the deuterium label.
• Material Science Research: Potential precursor for synthesizing specialized ionic liquids or functional materials where isotopic labeling is required for study.

Basic Information

Product Name	1-(Methyl-D3)-4-Phenylpyridinium Iodide
CAS No.	207556-07-8
Molecular Formula	C12H10D3IN
Molecular Weight	328.18 g/mol
Synonyms	1-(Trideuteriomethyl)-4-phenylpyridinium Iodide; N-(Methyl-d3)-4-phenylpyridinium Iodide; 4-Phenyl-1-(trideuteriomethyl)pyridinium Iodide; (Methyl-d3)triphenylphosphonium Iodide (common misnomer, related class); Deuteronated N-Methyl-4-phenylpyridinium Iodide; MPP+ Iodide (d3); N-Methyl-d3-4-phenylpyridinium Iodide
EINECS	Contact for details

Quality Control

Our 1-(Methyl-D3)-4-Phenylpyridinium Iodide is manufactured under strict quality protocols to ensure high isotopic purity and chemical integrity, meeting the stringent requirements of research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chemical purity (by HPLC/NMR), isotopic enrichment (D-content), and identity confirmation. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent oxidation and moisture uptake. Keep the container sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.