Description

Bicyclo[3.1.0]Hexane-2,6-Dicarboxylic Acid, 2-Amino-, (1R,2R,5S,6S)-Rel- (9Ci) is a high-purity, stereochemically defined bicyclic amino acid derivative that serves as a sophisticated chiral building block. Its rigid, fused-ring structure and multiple functional groups make it a critical intermediate for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily utilized by research and development teams in the pharmaceutical and advanced agrochemical sectors for drug discovery and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research.
• Peptidomimetic Design: Used to introduce conformational constraints into peptide backbones, enhancing metabolic stability and receptor selectivity.
• Ligand Synthesis for Catalysis: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Research: Employed in the synthesis of advanced, stereospecific herbicides and fungicides.
• Material Science: Potential monomer for creating novel polymers with unique thermal and mechanical properties.
• Academic & Contract Research: A valuable tool for methodological development in organic synthesis and medicinal chemistry.

Basic Information

Product Name	Bicyclo[3.1.0]Hexane-2,6-Dicarboxylic Acid, 2-Amino-, (1R,2R,5S,6S)-Rel- (9Ci)
CAS No.	207553-80-8
Molecular Formula	C9H11NO4
Molecular Weight	197.19 g/mol
Synonyms	(1R,2R,5S,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid; rel-(1R,2R,5S,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid; 2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (stereoisomer); Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1R,2R,5S,6S)-rel-; LY-404,039 intermediate; (1R,2R,5S,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid; Pomaglumetad intermediate
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality management systems. We employ state-of-the-art analytical techniques, including chiral HPLC and NMR, to ensure exceptional stereochemical purity and chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.