Description

Bicyclo[1.1.1]Pentan-1-Ol, 3-Bromo- (9Ci) is a highly functionalized, strained bicyclic organic compound that serves as a versatile and valuable synthetic intermediate. Its unique [1.1.1]propellane-derived structure, featuring a reactive bromine substituent and a hydroxyl group, makes it a critical building block for constructing complex molecular architectures. This compound is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in medicinal chemistry, ligand synthesis, and polymer cross-linking.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for creating three-dimensional, sp3-rich scaffolds in drug discovery programs.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where its strained ring system can impart unique biological activity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands for transition metal catalysis and organocatalysts.
• Advanced Material Monomer: Employed in polymer chemistry to introduce rigid, bicyclic units into polymer backbones, enhancing thermal and mechanical properties.
• Cross-coupling Reactions: The bromine atom is amenable to various metal-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) for carbon-carbon bond formation.
• Academic and R&D: A valuable reagent for methodological studies in organic synthesis, exploring new reactions involving strained systems.

Basic Information

Product Name	Bicyclo[1.1.1]Pentan-1-Ol, 3-Bromo- (9Ci)
CAS No.	207392-09-4
Molecular Formula	C5H7BrO
Molecular Weight	163.01 g/mol
Synonyms	3-Bromobicyclo[1.1.1]pentan-1-ol; 3-Bromo-1-hydroxybicyclo[1.1.1]pentane; 1-Bicyclo[1.1.1]pentanol, 3-bromo-; BCP-Br-OH; 3-Bromo-BCP-ol
EINECS	Contact for details

Quality Control

Every batch of Bicyclo[1.1.1]Pentan-1-Ol, 3-Bromo- is produced and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our standard offering meets high-purity specifications suitable for synthetic chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by GC/HPLC), and impurity profiles is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥95% (Standard Grade)
Purity (HPLC/GC)	≥98% (High Purity Grade)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.