Description

Boronic Acid, [1-(Triphenylmethyl)-1H-Pyrazol-4-Yl] is a specialized organoboron compound featuring a trityl-protected pyrazole core. This chemical is a critical synthetic intermediate valued for its role in cross-coupling reactions, particularly in the construction of complex pharmaceutical and agrochemical molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in kinase inhibitor and oncology research.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging the boronic acid functionality for carbon-carbon bond formation.
• Material Science Research: Serves as a precursor for creating organic electronic materials, metal-organic frameworks (MOFs), and functional polymers.
• Chemical Biology & Proteomics: Employed in the synthesis of activity-based probes and inhibitors for studying enzyme function and protein interactions.
• Catalyst Ligand Development: The pyrazole-boronic acid structure can be utilized to develop novel ligands for transition metal catalysis.
• Academic & Contract Research: Essential for methodological development in organic synthesis and for producing custom compounds in contract research organizations (CROs).

Basic Information

Product Name	Boronic Acid, [1-(Triphenylmethyl)-1H-Pyrazol-4-Yl]
CAS No.	207307-51-5
Molecular Formula	C24H21BN2O2
Molecular Weight	380.25 g/mol
Synonyms	[1-(Triphenylmethyl)-1H-pyrazol-4-yl]boronic acid; 1-Trityl-1H-pyrazole-4-boronic acid; 4-Borono-1-trityl-1H-pyrazole; (1-Trityl-1H-pyrazol-4-yl)boronic acid; 1-Trityl-4-pyrazoleboronic acid; 1H-Pyrazole-4-boronic acid, 1-(triphenylmethyl)-; B-[1-(Triphenylmethyl)-1H-pyrazol-4-yl]boronic acid
EINECS	Contact for details

Quality Control

Our Boronic Acid, [1-(Triphenylmethyl)-1H-Pyrazol-4-Yl] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.